Pancreatic cancer is an aggressive tumor with high metastatic potential which leads to decreased survival rate and resistance to chemotherapy and immunotherapy.Nearly 90% of pancreatic cancer comprises pancreatic ductal adenocarcinoma (PDAC).About 80% of diagnoses takes place at the advanced metastatic stage when it is unresectable, which renders c

AbstractOsteoporosis and bone fractures are a severe problem for the welfare of laying hens, with genetics and environment, such as housing system, each making substantial contributions to bone strength.In this work, we performed genetic analyses of bone strength, bone mineral density, and bone composition, as well as body weight, in 860 commercial

Ketamine is an NMDA receptor antagonist with psychotomimetic, dissociative, amnestic and euphoric effects.When chronically abused, ketamine users display deficits in cognition and information processing, even following long-term abstinence from the drug.While animal studies have shown evidence of behavioral changes and cognitive deficits that mimic

Background: Transient receptor potential cation channel subfamily V (TRPV) play an essential in cancer initiation, progression, and treatment.TRPV expression alteration are shown relate to multiple cancers prognosis and treatment of cancers but are less-studied in pan-cancer.In this study, we characterize the clinical prediction value of TRPV at pa

With start the coercive war, specially cities war, the everyday life of Iranian people arrived to a new level of perpetual stress.Since political system was responsible to run the problem of the war so it had arrived into the everyday life.This situation and how its effects and emerge its meaning on the lived experience of the member of the society